Figure 3.
Upregulation of LACTB reduced OXA-induced mitochondrial depolarization, glucose uptake and ATP synthesis of OXA-resistant MGC-803 cells. A. After LACTB overexpression, MGC-803/OXA cells were stained with JC-1 to evaluate mitochondrial depolarization by flow cytometry. B. The degree of mitochondria damage was examined by IF assay. Magnification 200 ×, Scale bars = 20 μm. C, D. The levels of 2-DG uptake and ATP were determined using the respective kits in LACTB overexpressed MGC-803/OXA cells. ***P < 0.001 vs. control group; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. blank group.
