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LACTB resulted in OXA-induced DNA damage by inhibiting autophagy pathway in MGC-803/OXA cells. A. IF assay was performed to assess the degree of LC3B. Magnification 200 ×, Scale bars = 20 μm. B. Markers of DNA double-stranded damage and autophagy were examined by Western blot assay in MGC-803/OXA cells after treatment with LACTB plasmid, RAPA or/and OXA. C-H. The relative gray density was counted by comparison with GAPDH. *P < 0.05; **P < 0.01, ***P < 0.001.
