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. 2021 Feb 8;47:24. doi: 10.1186/s13052-021-00980-2

HEART

c in case of coronary dilation, we recommend to refer to related AHA definitions [17]

Hypotension. Please consider that some patients with MIS-C may have

SHOCK as the presenting sign, or develop it rapidly during hospitalization. This shock is usually associated with capillary leak syndrome or is cardiogenic, without signs of hypoperfusion.

Myocarditis (in some cases there is only cardiac enzyme elevation, without ultrasound abnormalities)

Valvular insufficiency

Cardiac conduction abnormalities

Heart failure

Coronary abnormalitiesc

Respiratory

Nasal drip/congestion

Pharyngodynia/pharyngitis

Cough

Thoracic pain

Respiratory distress

Acute respiratory failure

Skin and mucous membranes

Polymorphous rash/perineal erythema

Erythema of the palms and soles /induration of the hands and feets

Cracked lips/strawberry tongue

Nonexudative conjunctival injection

Lymphnode enlargement

Kidney

Renal failure

Oliguria and/or anuria

Oedema

Gastrointestinal

Severe abdominal pain

Diarrhea

Nausea and/or vomiting

Jaundice

Musculoskeletal

Arthralgia

Myalgia

Arthritis

Central nervous system (CNS)

Headache

Irritability

Meningism

Confusion

Seizures