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. 2021 Jan 28;18(1):47–66. doi: 10.11909/j.issn.1671-5411.2021.01.007

2. Role of cardiac adrenergic receptors activation in heart failure progression.

Effects Receptor types Positive Negative
β1 Epicardial vessel vasodilation
Positive lusitropy
Positive chronotropy
Positive inotropy
Apoptosis
Proarrhythmic
Myocyte damage
Fetal gene induction
β2 Antiapoptotic
Small vessel vasodilation
Positive lusitropy
Positive chronotropy
Positive inotropy
Proarrhythmic
Profibrotic
α1c Positive inotropy Vasoconstriction
Proarrhythmic
Myocyte damage