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. 2017 Sep 20;52(6):629–637. doi: 10.1093/alcalc/agx063

Fig. 2.

Fig. 2.

Lieber-DeCarli ethanol + binge regimen induces the highest degree of liver injury independent of strain. (A) Representative images of liver sections from C57BL/6 (C57) and cHAP mice stained with hematoxylin and eosin (H&E). Mice were maintained on Lieber-DeCarli control liquid diet + maltose-dextrin (LDC+MD), Lieber-DeCarli ethanol liquid diet + Binge (LDE+B), or free access to 10% (v/v) ethanol in DW + binge (EtOH-DW+B). Yellow bars = 100 μm. (B) Representative sections from C57 and cHAP (cH) mice were blind scored for steatosis, inflammation and necrosis. (C) Triglyceride (TG) levels measured in hepatic tissue lysates. #P < 0.05 strain-matched LDE+B or EtOH-DW+B versus LDC+MD. †P < 0.05 strain-matched LDE+B versus EtOH-DW+B. ND, not detected.