Figure 6.

Bioinformatics analysis of sevoflurane altered lncRNA-related pathways based on the dysregulated lncRNA co-expressed dysregulated mRNAs using ingenuity pathway analysis (IPA) software. The figure displays how each of the sevoflurane-dysregulated mRNAs, which are highly correlated with their corresponding co-expressed dysregulated lncRNAs, are involved in top disease and function (A), as well as apoptosis and necrosis networks (B). Each symbol represents one individual gene. Solid and dotted lines show a direct and indirect connection between genes. Green symbols indicate downregulation and red indicate upregulation following sevoflurane exposure. The abbreviations of the genes were defined in Supplemental Table S3.