Table 1.
Dysregulated lncRNAs and their nearby coding mRNAs in PD7 mouse brains following 3% sevoflurane exposure for 6 h.
| lncRNA Symbol |
lncRNA Strand |
lncRNA | mRNA Symbol |
mRNA Strand |
Nearby Coding mRNA | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| p-Value 1 | Fold Change | Regulation | FDR | p-Value | Fold Change | Regulation | FDR | ||||
| Gm16287 | − | 0.00024 | 2.4 | up | 0.099 | Ubr4 | + | 0.042 | 2.1 | down | 0.32 |
| Ak048274 | + | 0.014 | 2.4 | up | 0.22 | Igfbp5 | - | 0.011 | 2.3 | down | 0.24 |
| Ak081961 | + | 0.000038 | 6.5 | up | 0.057 | Igfbp5 | - | 0.011 | 2.3 | down | 0.24 |
| Ak137249 | − | 0.0019 | 2.9 | up | 0.14 | Mall | - | 0.00013 | 2.5 | up | 0.078 |
| Ak138713 | − | 0.00093 | 2.3 | up | 0.12 | Xlr5b | + | 0.027 | 2.2 | up | 0.28 |
| A730032A03Rik | + | 0.039 | 2.9 | down | 0.28 | Slpi | - | 0.0018 | 3.4 | up | 0.17 |
Note: 1 p values and expression fold changes are displayed against air control group. FDR: false-discovery rate. The full gene names of the sevoflurane-induced dysregulated mRNAs are detailed in Supplementary Table S3.