TABLE 2.

Overrepresented associations in differentially expressed microRNAs (TAM 2.0).

Category	Term	FDR	microRNA
Input: Upregulated microRNAs in LSC-enriched CD34+CD38−CD26+ vs. CML-CP HSC fractions (miR-92b, miR-196a, miR-126, miR-125a, miR-2355, miR-99b, miR-411, miR-10a)
Function	Lipid metabolism	0.0141	hsa-mir-125a, hsa-mir-126, hsa-mir-196a-2, hsa-mir-196a-1
Function	Hematopoiesis	0.0217	hsa-mir-125a, hsa-mir-126, hsa-mir-196a-2, hsa-mir-196a-1
TF	EGR1	0.00704	hsa-mir-125a, hsa-mir-99b, hsa-mir-10a, hsa-mir-92b
Cluster	hsa-mir-99b cluster	0.0138	hsa-mir-99b, hsa-mir-125a
Input: downregulated microRNAs in LSC-enriched CD34+CD38−CD26+ vs. CML-CP HSC fractions (miR-708, miR-431, miR-134, miR-485, miR-409, miR-323b, miR-432, miR-382)
Cluster	hsa-mir-379 cluster	0.00248	hsa-mir-382, hsa-mir-134, hsa-mir-485, hsa-mir-323b, hsa-mir-409
Input: downregulated microRNAs in CML-CP HSC vs. HD HSC (excluding let-7 family) (miR-20a, miR-195, miR-654, miR-224, miR-144, miR-181c, miR-548o, miR-182, miR-183)
Function	Glucose metabolism	0.0514	hsa-mir-20a, hsa-mir-195, hsa-mir-144
Transcription factor	E2F1	0.0457	hsa-mir-20a, hsa-mir-224, hsa-mir-195
Transcription factor	STAT5	0.0557	hsa-mir-195, hsa-mir-20a

FDR, false discovery rate.

Only statistically significant results are shown.