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. 2021 Feb 8;10(4):e12067. doi: 10.1002/jev2.12067

FIGURE 9.

FIGURE 9

Summary of WJMSCs’ contribution to circulation PD‐L1 pool through secreting sEVs in aGvHD patients. Transplanted WJMSCs are induced by IFN‐γ and enhance the release of sEV‐carried PD‐L1 in the blood. Membrane‐bound sEV‐PD‐L1 interacts the PD1 on the T cells and modulate the TCR‐mediated TCA associated with aGvHD