Table 2.

Significant correlations of radiomics features with immunoprofiling features in 48 HCCs

Marker	Radiomics feature	r	FDR-adj p
CD3	Qualitative features
	Tumour fat content	− 0.41	0.019
CD31	Texture features
	Pre variance 16 bins	− 0.47	0.005
	Pre information measure of correlation 2 16 bins	−0.38	0.038
	LAP maximal correlation 16 bins	−0.52	0.003
	Pre variance 64 bins	−0.47	0.005
	Quantitative features
	ERLVP	0.37	0.023
CD68	Texture features
	Pre variance 16 bins	0.33	0.047
	Pre sum average 16 bins	0.41	0.018
	Pre sum variance 16 bins	0.41	0.018
	Pre sum average 64 bins	0.37	0.049
	Pre sum variance 64 bins	0.42	0.017
	EAP sum entropy 64 bins	0.45	0.049
	Qualitative features
	Mosaic appearance	0.40	0.023
	Wash-in/wash-out	0.37	0.042
PD-L1	Texture features
	ADC variance 64 bins	0.41	0.029
	Quantitative features
	ERPVP	0.42	0.015
	ER LVP	0.47	0.005

Correlation coefficient coefficients (r) resulted from Spearman correlation analysis. p values were adjusted for multiple tests using a false discovery rate (FDR) adjustment

ADC = apparent diffusion coefficient, AUC = area under the curve, EAP = early arterial phase, ER = enhancement ratio, LAP = late arterial phase, LVP = late venous phase, PVP = portal venous phase