Table 2. Logistic regression analysis of variables: adjusted odds ratios for mortality outcome ( n = 2,450) .
Variable | Odds ratio | 95% Confidence interval | p- Value |
---|---|---|---|
Age, y | |||
< 50 | 1 | ||
50–60 | 2.71 | 1.57–4.71 | < 0.001 |
60–70 | 4.9 | 2.43–6.91 | < 0.001 |
70–80 | 5.85 | 3.45–9.92 | < 0.001 |
≥ 80 | 8.59 | 5.01–14.74 | < 0.001 |
Oxygen saturation, % | |||
> 95% | 1 | ||
90–95% | 1.56 | 1.18–2.05 | 0.002 |
< 90% | 3.25 | 2.45–4.28 | < 0.001 |
eGFR mL/min | |||
> 60 | 1 | ||
≥ 30–60 | 1.76 | 1.33–2.33 | < 0.001 |
15–30 | 2.61 | 1.84–3.69 | < 0.001 |
0–15 | 1.85 | 1.28–2.67 | < 0.001 |
D-dimer, µg/mL | |||
< 1 | 1 | ||
1–3 | 1.81 | 1.30–2.52 | < 0.001 |
3–10 | 2.24 | 1.54–3.27 | < 0.001 |
≥ 10 | 3.46 | 2.31–5.19 | < 0.001 |
Time period | |||
First time period | 1 | ||
Wave | 0.53 | 0.41–0.68 | < 0.001 |
ICU | |||
No ICU | 1 | ||
ICU | 3.72 | 2.50–5.52 | < 0.001 |
Medication and regimen, intent type | |||
No anticoagulation | 1 | ||
Apixaban prophylaxis | 0.46 | 0.30–0.71 | 0.001 |
Apixaban full therapy | 0.57 | 0.38–0.85 | 0.006 |
Enoxaparin prophylaxis | 0.49 | 0.32–0.73 | 0.001 |
Enoxaparin full therapy | 0.83 | 0.44–1.56 | 0.57 |
UFH prophylaxis twice daily | 0.79 | 0.54–1.17 | 0.24 |
UFH prophylaxis thrice daily | 1.04 | 0.54–1.17 | 0.91 |
UFH full therapy | 0.97 | 0.51–1.84 | 0.93 |
Abbreviations: eGFR, estimated glomerular filtration rate; ICU, intensive care unit; UFH, unfractionated heparin.