. Author manuscript; available in PMC: 2021 Feb 8.

Published in final edited form as: J Cardiovasc Transl Res. 2020 Apr 4;13(3):367–376. doi: 10.1007/s12265-020-09981-8

Table 2:

CMR-derived tissue characterization changes representative of cardiomyocyte and interstitial remodeling in response to potential cardiotoxic chemotherapy

CMR Tissue Characterization Technique	Cardiomyocyte Atrophy & Edema	Cardiomyocyte Atrophy & Fibrosis	Cardiomyocyte Hypertrophy & Fibrosis
T1	↑	↑	↑
ECV	↑	↑	↑
T2	↑	-	↓/-
τic	↓	↓	↑

CMR parameters (T1, ECV, T2, τic) and their direction of change associated with cardiomyocyte and interstitial features as indicated by an increase (up arrow), decrease (down arrow), or no change (dash). Arrow and dashes in bold represent the tissue characteristic that determines the nature of the remodeling process and ECV expansion.