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. Author manuscript; available in PMC: 2021 Feb 8.
Published in final edited form as: Hosp Pediatr. 2019 May;9(5):340–347. doi: 10.1542/hpeds.2018-0265

TABLE 3.

Neonatal Antimicrobial Stewardship Targets and Proposed SAAR Antimicrobial Agent Categories

Neonatal ASP Target SAAR Agent Category Antimicrobials Included Routes of Administration NHSN Units Included
Empiric treatment of late-onset sepsis Vancomycin Vancomycin IV II, II-III, III
Broad spectrum treatment of bacterial infections Broad spectrum antibacterial agents Piperacillin and/or tazobactam IV II, II-III, III
Cefepime
Ertapenem
Meropenem
Imipenem and/or cilastatin
Prophylaxis and treatment of invasive candidiasis Fluconazole Fluconazole IV, oral II, II-III, III
Global or total antibiotic use All antibacterial agents All antibacterial agents in AU option IV, IM, oral, respiratory II, II-III, III
Empiric treatment of early-onset sepsis Ampicillin Ampicillin IV All
Cefotaxime,Ceftazidime Cefotaxime IV All
Ceftazidime
Empiric treatment of early-onset and late-onset sepsis Aminoglycosides Gentamicin IV All
Tobramycin
Amikacin

IM, intramuscular; IV, intravenous.