Table 2.
Identified metabolites with significant differences between NBW and IUGR pigsa
| No. | Description | MS b | Formula | Fold change c | P-value |
|---|---|---|---|---|---|
| 1 | Proline | 115.1307 | C5H9NO2 | 1.40 | < 0.05 |
| 2 | Arginine | 175.0701 | C6H14N4O2 | 1.82 | < 0.05 |
| 3 | Valine | 117.0812 | C5H11NO2 | 1.32 | < 0.05 |
| 4 | Ornithine | 133.1601 | C5H12N2O2 | 2.29 | < 0.05 |
| 5 | Threonine | 120.0644 | C4H9NO3 | 2.31 | < 0.05 |
| 6 | 5-Aminopentanoic acid | 117.1513 | C5H11NO2 | 0.46 | < 0.05 |
| 7 | Lysine | 147.1305 | C6H14N2O2 | 0.79 | < 0.05 |
| 8 | Pipecolic acid | 129.1357 | C6H11NO2 | 0.76 | < 0.05 |
| 9 | Palmitelaidic acid | 254.2382 | C16H30O2 | 2.11 | < 0.05 |
| 10 | Oleic acid | 282.7423 | C18H34O2 | 1.65 | < 0.05 |
aNBW normal birth weight, IUGR intrauterine growth restriction, n = 12
bActual M-to-Z ratio
cFold change was calculated by dividing the mean of normalized intensity of each plasma metabolite in the former by the mean of normalized intensity of each plasma in the latter. Fold change > 1 indicates that the metabolite was up-regulated in NBW pigs, whereas fold change < 1 indicates the metabolite was down-regulated