miRs	genes/pathways targeted	effect on bone growth/regeneration
miRs-29a, −146a	RANKL-RANK-OPG	inhibition of bone resorption (OVX model)
miRs-139, −145, −26a, −451 and −100	osteogenic signals	increase osteoporosis (OVX model)
miRs-199a, −219a, −208a	osteogenic signals	improve osteogenesis
miRs-23b, −103a	RUNX2	inhibit bone formation (OVX model)
miRs-146a, −200c	inflammation, IL6, IL-1B, TNF-a	inhibition of pro-inflammatory cytokines
miR-200c	inflammation, IL-6, IL-8, CCL-5	inhibition of pro-inflammatory cytokines
miRs-375, −101, −450b, −135, −218, −335, −199a, −99a	BMP, IGF, WNT	regenerate bone tissue, increase osteogenic differentiation
miRs-133a, −137, −31	RUNX2, BMP	bone progenitor cell differentiation
miRs-146a, −21,−221	SMADs	osteogenic differentiation
miRs-138, −124	FAK, DLX	increase osteogenic differentiation