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. 2021 Feb 8;115:103696. doi: 10.1016/j.jbi.2021.103696

Table 4.

Comparison of drug overlap between methods and studies.

Methods Common Drugs
Zeng et al. [16]
TransE
Discovery Patterns
Estradiol
Zeng et al. [16]
Singh et al. [94]
RotatE
Dexamethasone
Zeng et al. [16]
Discovery Patterns
Hydrocortisone
Indomethacin
Zeng et al. [16]
STELP
Zidovudine
TransE
STELP
5-alpha Reductase Inhibitors
RotatE
STELP
Pibrentasvir
Anti-ILDR2 Monoclonal-
Antibody BAY 1905254
Mood Stabilizer
Opium alkaloids and-
derivative combination-
cough suppressants
Valoctocogene roxaparvovec
RotatE
Discovery Patterns
Paclitaxel

Note: Drugs are from the top 50 ranked drugs from RotatE, STELP, the 33 drugs from TransE identified by MF as plausible, and the drugs specified in Zeng et al. [16], Zhou et al. [14], and Singh et al. [94]. We also use top 50 drugs identified using the discovery pattern in open discovery mode.