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. 2021 Feb 5;9:e10805. doi: 10.7717/peerj.10805

Table 3. Syncmers with higher compression and higher conservation than minimizers with minimap2 parameters.

Minimap2 uses minimizers with k = 15, w = 10. This table shows syncmers having both higher compression (lower density) and higher conservation than minimizers with these parameters, which are shown in the first row for comparison. Rows are sorted by increasing conservation. OR indicates whether the syncmers are open (Yx) or closed (Nx), and whether they are rotated (xY) or not (xN). Notice for example that open syncmers with s = 9, t = 3 achieve compression of 7.0 vs. 5.5 for minimizers (27% lower density) with conservation of 0.312 vs. 0.301 (4% better).

w s t OR c Cons90 Cons80
10 5.5 0.301 0.060
1 2 YN 7.0 0.302 0.062
1 2 YY 7.0 0.302 0.062
10 YN 6.0 0.306 0.064
10 5 YN 6.0 0.306 0.064
4 NN 6.0 0.306 0.063
1 2 NY 6.8 0.308 0.064
9 4 YN 7.0 0.308 0.063
9 2 YN 7.0 0.309 0.064
9 3 YN 7.0 0.312 0.064
10 4 YN 6.0 0.323 0.069
10 1 YN 6.0 0.324 0.068
10 2 YN 6.0 0.333 0.071
10 3 YN 6.0 0.333 0.071