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. 2021 Feb 5;9:e10805. doi: 10.7717/peerj.10805

Table 6. Maximum distances under mutations.

Maximum distance for minimap2-like and Kraken-like minimizers compared to selected syncmers on random sequences of length 1 M and 100 M at identities of 95% and 90%. For k = 15, these are open syncmers with s = 9 and offset t = 4; for k = 31 they are open syncmers with s = 21, t = 5. Neither of these syncmer types has a window guarantee. In identical sequences, the minimizers have a window size of 10 (k = 15) and 16 (k = 31), but under mutation the maximum spacing is much greater, even at 95% identity. Syncmers often have lower maximum spacing under mutation despite the lack of a window guarantee.

k L (M) %Id Max dist.
minimizer
Max dist.
syncmer
15 1 95 215 197
15 1 90 444 439
15 100 95 293 294
15 100 90 693 688
31 1 95 809 705
31 1 90 3,906 4,207
31 100 95 1,277 1,094
31 100 90 4,898 4,837