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. Author manuscript; available in PMC: 2021 Feb 8.
Published in final edited form as: Nat Genet. 2020 Feb 24;52(3):264–272. doi: 10.1038/s41588-020-0581-x

Extended Data Fig. 7: Upregulation of genes associated with si-Δchr7.

Extended Data Fig. 7:

PRC2 interaction and binding profiles of the 1 Mb Igf2/Kcnq1 imprinting region. The si-Δchr7 (chr7:143,440,438–143,450,716) is marked in red. Three of the 10 genes with P-I interactions to this KO region located 15.5 Mb upstream. b. Normalized RNA-seq counts of the connected genes in wild type (+/+) (n=3) and 2 independent homozygous KO (−/−) ES clones D4 (n=3) and F4 (n=3). Gm44732 has no expression. N indicates number of biologically independent samples.