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. Author manuscript; available in PMC: 2021 Feb 8.
Published in final edited form as: Nat Genet. 2020 Feb 24;52(3):264–272. doi: 10.1038/s41588-020-0581-x

Extended Data Fig. 3: Experimental validation of intergenic silencers in vivo.

Extended Data Fig. 3:

a. Schematic overview of generating heterozygous founder mice strains and ES clones carrying deletion in the intergenic anchors by CRISPR/Cas9. b. Schematic description of genotype strategy and primer design used in screening of KO mice and derived ES clones.