Table 2.
KPT2D | T2D | P | P Adjusted | |
---|---|---|---|---|
Glucose | ||||
Fasting glucose (mmol/L) | 13.3 ± 0.2 | 9.1 ± 0.2 | <0.0001 | <0.0001 |
Postprandial 2-h glucose (mmol/L) | 20.1 ± 0.3 | 13.9 ±0.3 | <0.0001 | <0.0001 |
Hemoglobin A1c (%) | 12.0 ± 0.1 | 9.8 ± 0.1 | <0.0001 | <0.0001 |
Fasting C-peptide (nmol/L) | 0.53 (0.40–0.76) | 0.71 (0.54–1.1) | <0.0001 | <0.0001 |
Postprandial 2-h C-peptide (nmol/L) | 0.79 (0.56–1.24) | 1.80 (1.18–2.41) | <0.0001 | <0.0001 |
Δ C-peptide (nmol/L) | 0.26 (0.08–0.57) | 0.98 (0.46–1.50) | <0.0001 | <0.0001 |
Lipids | ||||
Serum triglycerides (mmo/L) | 2.31 (1.57–4.72) | 1.89 (1.33–3.36) | <0.0001 | 0.0003 |
Serum total cholesterols (mmo/L) | 5.2 ± 0.1 | 4.9 ± 0.1 | 0.02 | 0.05 |
HDL-cholesterol (mmo/L) | 1.06 ± 0.02 | 1.13 ± 0.02 | 0.02 | 0.08 |
LDL-cholesterol (mmo/L) | 2.91 ± 0.06 | 2.71 ± 0.05 | 0.02 | 0.22 |
Liver enzymes | ||||
Alanine aminotransferase (U/L) | 63.1 ± 3.8 | 53.5 ± 4.0 | 0.08 | 0.44 |
Aspartate aminotransferase (U/L) | 43.5 ± 2.8 | 34.3 ± 2.9 | 0.02 | 0.15 |
Renal function | ||||
Serum creatinine (μmol/L) | 81.5 ± 1.2 | 79.8± 1.2 | 0.08 | 0.44 |
Serum uric acid (μmol/L) | 377 ± 9 | 360 ± 9 | 0.17 | 0.54 |
Notes: Values are presented with means ± SEM, %. Serum TGs and C-peptides have been presented as median (interquartile range, IQR). P: KPT2D versus T2D. P adjusted: KPT2D versus T2D adjusted by age and sex.
Abbreviations: KPT2D, ketosis-prone type 2 diabetes; T2D, type 2 diabetes with ketosis.