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. 2021 Feb 4;14:497–504. doi: 10.2147/DMSO.S296085

Table 2.

The Laboratory Results of the KPT2D and T2D Subjects

KPT2D T2D P P Adjusted
Glucose
Fasting glucose (mmol/L) 13.3 ± 0.2 9.1 ± 0.2 <0.0001 <0.0001
Postprandial 2-h glucose (mmol/L) 20.1 ± 0.3 13.9 ±0.3 <0.0001 <0.0001
Hemoglobin A1c (%) 12.0 ± 0.1 9.8 ± 0.1 <0.0001 <0.0001
Fasting C-peptide (nmol/L) 0.53 (0.40–0.76) 0.71 (0.54–1.1) <0.0001 <0.0001
Postprandial 2-h C-peptide (nmol/L) 0.79 (0.56–1.24) 1.80 (1.18–2.41) <0.0001 <0.0001
Δ C-peptide (nmol/L) 0.26 (0.08–0.57) 0.98 (0.46–1.50) <0.0001 <0.0001
Lipids
Serum triglycerides (mmo/L) 2.31 (1.57–4.72) 1.89 (1.33–3.36) <0.0001 0.0003
Serum total cholesterols (mmo/L) 5.2 ± 0.1 4.9 ± 0.1 0.02 0.05
HDL-cholesterol (mmo/L) 1.06 ± 0.02 1.13 ± 0.02 0.02 0.08
LDL-cholesterol (mmo/L) 2.91 ± 0.06 2.71 ± 0.05 0.02 0.22
Liver enzymes
Alanine aminotransferase (U/L) 63.1 ± 3.8 53.5 ± 4.0 0.08 0.44
Aspartate aminotransferase (U/L) 43.5 ± 2.8 34.3 ± 2.9 0.02 0.15
Renal function
Serum creatinine (μmol/L) 81.5 ± 1.2 79.8± 1.2 0.08 0.44
Serum uric acid (μmol/L) 377 ± 9 360 ± 9 0.17 0.54

Notes: Values are presented with means ± SEM, %. Serum TGs and C-peptides have been presented as median (interquartile range, IQR). P: KPT2D versus T2D. P adjusted: KPT2D versus T2D adjusted by age and sex.

Abbreviations: KPT2D, ketosis-prone type 2 diabetes; T2D, type 2 diabetes with ketosis.