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Comparison of the AUC-ROC scores across the six independent validation datasets based on the test signature, identified by the proposed meta-analysis framework–GSMA versus using one given discovery dataset at a time. Here, the median AUC-ROC score obtained by GSMA is significantly higher (P-value = 0.0003) than all other median AUC-ROC scores obtained on any individual dataset. This comparison shows that the proposed meta-analysis yield better results that any single analysis
