Table 3. Observed and expected genotypes for the Tg(Drd1a-Cre)120MXu mouse line.
| F2 Possible Genotypes | Expected | Observed |
|---|---|---|
| WT D1R/flox D1R; D1R-Cre + | 11.75 | 23 |
| WTD1R/flox D1R; D1R-Cre – | 11.75 | 15 |
| Flox D1R/flox D1R; D1R-Cre – | 11.75 | 9 |
| Flox D1R/flox D1R; D1R-Cre + | 11.75 | 0 |
Four possible genotypes were expected as a result of crossing D1Rwt/flox, D1R-Cre+ and D1Rflox/flox, D1R-Cre–mice. Of 47 offspring observed, an expected offspring of 11.75 for each genotype did not match observed, yielding a Chi-square statistic of 24.064 (P<0.0001, Chi-Square).