Table 3.

Performance specifications for genotyping on the ONT MinION. PPV: Positive Predictive Value; NPV: Negative Predictive Value.

Metric	HLA-A	HLA-B	HLA-C	HLA-DPA1	HLA-DPB1	HLA-DQA1	HLA-DQB1	HLA-DRB1	HLA-DRB3/4/5	Total
Sensitivity	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	98.33%	99.58%	98.75%	99.63%
Specificity	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	99.96%	99.99%	99.93%	99.99%
PPV (Precision)	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	99.16%	99.58%	98.75%	99.72%
NPV	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	99.92%	99.99%	99.93%	99.99%
Accuracy	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	99.89%	99.98%	99.86%	99.98%