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. 2020 Jan 8;42(1):1–8. doi: 10.1097/PAF.0000000000000664

FIGURE 3.

FIGURE 3

Comparison of microscopic lung findings in asymptomatic carriers with those with aggressive, symptomatic infections. Postmortem lung sections with no significant histology findings in decedents whose deaths were attributed to intoxication as compared with deaths attributed to COVID-19 infection, which are characterized by DAD. A, Case 8: low-power view of a decedent who died of fentanyl toxicity who incidentally tested positive for COVID-19 (H&E, original magnification ×2). B, Case 7: low-power view of the lungs of a chronic alcoholic who reported fever, cough, and feeling unwell before collapsing at home demonstrating congested intra-alveolar airspaces containing hyaline membranes, pulmonary edema, type II pneumocytes hyperplasia, macrophages, and fibrin (H&E, ×10). C, Case 9: high-power view of the lungs of a decedent who died of acute ethanol intoxication but tested positive for COVID-19 (H&E, ×40). D, Case 4: high-power view of extensive DAD with hyaline membrane formation, type II pneumocyte hyperplasia, pulmonary edema in a man with uncontrolled diabetes mellitus and chronic ethanolism who reported fever, cough, sore throat, dyspnea, and chest pain before death (H&E, ×40).