TABLE 2.
Publication Date | Authors | City | State | Setting | n | Mean Age, y | Organs Studied and/or Reported | Major Histologic Findings | |
---|---|---|---|---|---|---|---|---|---|
1 | 04/10/2020 | Barton et al17 | Oklahoma City | OK | Community | 2 | 59.5 | Lungs, heart, kidneys, liver, brain | DAD in only the COVID death |
2 | 04/15/2020 | Yan et al18 | San Antonio | TX | Hospital | 1 | 44 | Lungs, heart, kidney (by biopsy) | DAD, pulmonary infarct |
3 | 04/21/2020 | Paniz-Mondolfi et al19 | New York | NY | Hospital | 1 | 74 | Brain | Viral particles in endothelial cells |
4 | 04/28/2020 | Konopka et al20 | Ann Arbor | MI | Hospital | 1 | 37 | Lungs | DAD and mucus plugs |
5 | 05/07/2020 | Buja et al21 | Houston | TX | Mixed | 3 | 48 | Lungs, heart, kidneys, liver, spleen | DAD, microthrombi common but not universal, PEs common |
6 | 05/21/2020 | Ackermann et al22 | Boston | MA | Hospital | 7 | 78.4 | Lungs | Vascular thrombosis with microangiopathy, angiogenesis, endothelialitis |
7 | 05/24/2020 | Reichard et al23 | Rochester | NY | Hospital | 1 | 71 | Brain | Lack of typical features of viral and postviral encephalitides |
8 | 05/27/2020 | Fox et al24 | New Orleans | LA | Hospital | 10 | 63 | Lungs and heart | Thrombotic microangiopathy limited to the lungs, lack of secondary lung infection |
9 | 05/2020 | Martines et al25 | — | WA | Hospital | 8 | 73.5 | Lungs | Varying DAD with no correlation with symptom duration |
10 | 06/15/2020 | Konopka et al26 | Ann Arbor | MI | Community | 4 | 53 | Lungs | DAD |
11 | 06/19/2020 | Schaefer et al27 | Boston | MA | Hospital | 7 | 66 | Lungs | DAD with pneumocyte hyperplasia |
12 | 06/25/2020 | Rapkiewicz et al28 | New York | NY | Hospital | 7 | 57.4 | Lungs, heart, kidneys, liver, bone | Megakaryocytes in the vascular beds of lungs and heart, 2 cases of myocardial venous thrombosis |
13 | 07/02/2020 | Sauter et al29 | New York | NY | Hospital | 8 | 57.5 | Lungs | Thrombi, microthrombi |
14 | 07/16/2020 | Bradley et al30 | Seattle, Everett | WA | Hospital | 14 | 73.5 | Lungs, heart, kidneys, liver, brain | One case of lymphocytic myocarditis |
15 | 09/02/2020 | De Michele et al31 | New York | NY | Hospital | 40 | 71.5 | Lungs | Acute lung injury and nonacute lung injury patterns found |
Mean | 7.6 | 61.8 |
n, sample size; PE, pulmonary emboli.