Table 2. MbA proteins homologous to U. maydis effector genes with known virulence function.

Name	Homologue	Query cover	E-value	Identity (%)	U. maydis knockout phenotype	Reference
g1653	UMAG_01987 (Pep1)	82%	3-e56	60.96	Complete loss of tumor formation – blocked in early stages of infection	Doehlemann et al., 2009
g1828	UMAG_01829 (Afu1)	99%	0.0	71.57	Organ-specific effector – reduced virulence in seedling leaves	Schilling et al., 2014
g2626	UMAG_12197 (Cce1)	98%	1e-48	60.16	Complete loss of tumor formation – blocked in early stages of infection	Seitner et al., 2018
g2765	UMAG_11938 (Scp2)	100%	1e-73	93.44	Reduced in virulence	Krombach et al., 2018
g2910	UMAG_02475 (Stp1)	32%	3e-42	60.71	Complete loss of tumor formation – blocked in early stages of infection	Schipper, 2009
g3652	UMAG_02239 (See1)	43%	9e-11	54.90	Organ-specific effector – reduced virulence in seedling leaves	Redkar et al., 2015
g3113	UMAG_01375 (Pit2)	*	*	*	Complete loss of tumor formation – blocked in early stages of infection	Doehlemann et al., 2011
g3279	UMAG_03274 (Rsp3)	10%	5e-20	70.11	Strong attenuation of virulence – reduced tumor size and number	Ma et al., 2018
g5296	UMAG_05731 (Cmu1)	98%	3e-70	43.84	Reduced virulence	Djamei et al., 2011
g6183	UMAG_06098 (Fly1)	100%	0.0	81.85	Reduced virulence	Ökmen et al., 2018
g5835	UMAG_05302 (Tin2)	87%	8e-24	37.81	Minor impact on tumor formation – reduced anthocyanin biosynthesis	Brefort et al., 2014