Table 3. Parameters of the simulated cohort (Figure 3C).

Parameter	Explanation	Value
${\sigma }^2$	Magnitude of clone size fluctuations	0.08/year
d	Death rate	0.2/year
$\gamma$	Recruitment to proliferation ratio	0.1
$\theta$	Recruitment rate	105/year
$p_{0,-}$	Zero insertion fraction early in life	0.07
$p_{0,+}$	Adult zero insertion fraction	0.02
$t^{†}$	Time of recombination statistics switch	0.05 years
$N_{sample}$	Simulated sample size	5 ⋅ 105