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(A) ROC Curve analyses confirmed the uselessness of the CA 125 for PVD (sensitivity = 80%, specificity = 24%; AUC = 0.561). (B) In the HE4 ROC Curve analysis, using a cut-off of 90 pmol/L sensitivity was greatly improved (sensitivity = 76%, specificity= 88%; AUC = 0.741).
