Table 1.
Demographic characteristics, Clinical symptoms, and Comorbidities of patients on admission.
| Clinical characteristics | Severe-critically ill (n = 84) | Mild-moderate (n = 499) | P value |
| Age, yr | 57.0 (49.0–65.7) | 47.0 (33.0–56.0) | <.001 |
| Age groups | <.001 | ||
| <50 | 25 (29.8) | 296 (59.3) | |
| 50–64 | 37 (44.0) | 146 (29.3) | |
| ≥ 65 | 22 (26.2) | 57 (11.4) | |
| Female | 34 (40.5) | 232 (46.5) | .306 |
| Smokers | 8 (9.5) | 52 (10.4) | .802 |
| Exposure | .447 | ||
| Local residents of Wuhan | 5 (5.9) | 43 (8.6) | |
| Recently been to Wuhan | 6 (7.1) | 34 (6.8) | |
| Contacted with people from Wuhan | 33 (39.3) | 146 (29.3) | |
| Contacted with COVID-19 patients | 39 (46.4) | 241 (48.3) | |
| Unknown | 1 (1.2) | 35 (7.0) | |
| Symptoms on admission | |||
| Fever | 58 (69.0) | 289 (57.9) | .054 |
| The highest temperature (°C) | .126 | ||
| <37.3 | 26 (31.0) | 210 (42.1) | |
| 37.3–37.5 | 14 (16.7) | 89 (17.8) | |
| 37.5-38 | 15 (17.9) | 84 (16.8) | |
| 38.1–39.0 | 17 (20.2) | 79 (15.8) | |
| >39.0 | 12 (14.3) | 37 (7.4) | |
| Cough | 48 (57.1) | 312 (62.5) | .348 |
| Sputum | 20 (23.8) | 99 (20.3) | |
| Sore throat | 6 (7.1) | 39 (7.8) | .831 |
| Nasal congestion | 2 (2.4) | 22 (4.4) | .557 |
| Headache | 5 (6.0) | 20 (4.0) | .386 |
| Hemoptysis | 3 (3.6) | 6 (1.2) | .127 |
| Shortness of breath | 26 (31.0) | 37 (7.4) | <.001 |
| Chest pain | 2 (2.4) | 5 (1.0) | .267 |
| Fatigue | 32 (38.1) | 162 (32.5) | .311 |
| Chill | 8 (9.5) | 43 (8.6) | .786 |
| Nausea or vomiting | 3 (3.6) | 14 (2.8) | .723 |
| Mylgia or arthralgia | 14 (16.7) | 50 (10.0) | .071 |
| Diarrhea | 9 (10.7) | 30 (6.0) | .111 |
| Throat congestion | 4 (4.8) | 35 (7.0) | .445 |
| Comorbidities | |||
| Any | 48 (57.1) | 186 (37.3) | .001 |
| Hypertension | 27 (32.1) | 89 (17.8) | .002 |
| Diabetes | 25 (29.8) | 45 (9.0) | <.001 |
| COPD | 7 (8.3) | 10 (2.0) | .006 |
| Coronary heart disease | 6 (7.1) | 12 (2.4) | .033 |
| Cerebrovascular disease | 5 (6.0) | 5 (1.0) | .008 |
| Arrhythmia | 2 (2.4) | 9 (1.8) | .664 |
| Fatty liver | 3 (3.6) | 15 (3.0) | .734 |
| Hyperlipidemia | 1 (1.2) | 7 (1.4) | 1.000 |
| Anemia | 5 (6.0) | 10 (2.0) | .51 |
| Hepatitis B infection | 1 (1.2) | 16 (3.2) | .489 |
| Chronic renal disease | 1 (1.2) | 3 (0.6) | .464 |
| Cancer | 6 (7.1) | 4 (0.8) | .001 |
| Connective tissue disease | 2 (2.4) | 3 (0.6) | .153 |
| Pregnancy | 1 (1.2) | 2 (0.4) | .374 |
| Timeline (d) | |||
| Time from onset to admission | 5.8 (2.2–9.4) | 6.0 (2.3–10.7) | 0.696 |
| Hospital stay | 22.0 (12.0–32.75) | 16.0 (9.75–25.0) | 0.003 |
| Time from onset to severe disease | 7.0 (4.0–9.5) | ||
| Time from onset to critically ill disease | 10.0 (7.5–12.0) | ||