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(A) Schematic representation of designs of whole-cell biosensors based on the total vector (POLA). (B) Fluorescence appearance of the bacterial biosensor exposed different concentrations of arsenite. Reprinted from Pola-López L, Camas-Anzueto J, Martínez-Antonio A, et al. Novel arsenic biosensor “POLA” obtained by a genetically modified E. coli bioreporter cell. Sens Actuators B Chem. 2018;254:1061–1068. Copyright 2018, with permission from Elsevier.109
