Table 2. Conventional echocardiographic parameters in the high-dose prednisolone group.
| Median |
||||||
|---|---|---|---|---|---|---|
| Day 0 | Day 7 | Day 28 | Day 56 | Day 84 | ||
| B-mode | ||||||
| IVSd (mm) | 7.77 (5.81–9.43) | 7.81 (6.97–10.99) | 9.10 (6.80–9.69) | 9.64** (7.78–11.18) | 9.50** (8.18–10.80) | |
| IVSs (mm) | 11.67 (8.20–13.70) | 12.83 (9.40–18.40) | 12.70 (10.60–15.20) | 13.32** (11.80–15.40) | 13.25* (10.90–15.60) | |
| LVFWd (mm) | 7.64 (5.49–10.45) | 7.85 (5.67–9.73) | 7.44 (6.23–10.31) | 8.32* (6.91–10.88) | 8.34 (6.64–11.11) | |
| LVFWs (mm) | 12.02 (9.80–13.20) | 13.33 (11.30–16.30) | 12.79 (10.40–16.90) | 14.09** (10.20–16.60) | 12.72* (11.80–15.90) | |
| LVIDd (mm) | 30.86 (25.44–34.65) | 31.82 (27.22–34.22) | 31.82 (28.92–35.06) | 31.37 (28.66–35.34) | 31.04 (28.34–32.47) | |
| LVIDs (mm) | 19.97 (12.26–24.06) | 17.74 (9.62.–24.32) | 19.16 (14.54–23.51) | 18.08 (12.97–23.90) | 18.64 (14.64–25.47) | |
| EF (mm) | 68.50 (33.96–84.74) | 76.57 (50.54–93.22) | 72.66 (52.97–84.12) | 77.55* (60.17–87.35) | 71.98 (40.57–86.13) | |
| FS (mm) | 38.13 (15.42–51.92) | 44.13 (24.88–64.55) | 41.06 (26.33–51.68) | 45.16 (31.28–55.52) | 40.00 (19.07–54.25) | |
| RWT | 0.54 (0.43–0.55) | 0.50 (0.42–0.61) | 0.51 (0.48–0.60) | 0.54 (0.49–0.65) | 0.55* (0.51–0.67) | |
| LVM (g) | 61.88 (42.42–71.03) | 63.64 (57.04–74.57) | 69.40** (52.86–86.92) | 80.12** (64.47–88.19) | 71.31** (58.76–87.35) | |
| LA/AO | 1.08 (0.94–1.24) | 1.07 (0.88–1.30) | 1.15 (0.93–1.37) | 1.11 (1.04–1.39) | 1.13 (0.77–1.47) | |
| Pulse-doppler-mode | ||||||
| E velocity (cm/sec) | 97.5 (78.0–133.0) | 98.8 (89.0–110.0) | 103.5 (91.0–155.0) | 116.3* (111.0–125.0) | 113.0 (106.0–121.0) | |
| E decel time (msec) | 99.88 (62.35–109.70) | 81.15 (66.95–101.19) | 98.66 (74.47–113.65) | 90.55 (79.24–108.02) | 80.50 (71.36–95.72) | |
| A velocity (cm/sec) | 57.2 (41.0–82.0) | 62.7 (51.0–84.0) | 72.8* (52.0–109.0) | 85.0** (60.0–94.0) | 76.2* (59.0–89.0) | |
| E/A | 1.63 (1.31–2.43) | 1.58 (1.32–2.00) | 1.46 (1.24–1.93) | 1.41 (1.24–1.91) | 1.50 (1.24–1.82) | |
| AO velocity (m/sec) | 1.45 (0.84–1.62) | 1.38 (1.20–1.56) | 1.59* (1.40–1.96) | 1.43 (1.39–1.73) | 1.45 (1.13–1.69) | |
| PEP/ET | 0.40 (0.23–0.43) | 0.38 (0.34–0.43) | 0.35 (0.31–0.47) | 0.37 (0.26–0.53) | 0.46* (0.37–0.50) | |
| ICT (msec) | 38.50 (28.55–68.51) | 37.13 (28.50–48.20) | 39.96 (19.98–45.00) | 37.10 (20.42–43.01) | 31.63 (22.83–62.80) | |
| IRT (msec) | 49.95 (28.54–68.50) | 38.54 (25.49–48.53) | 38.46 (25.69–51.12) | 39.96 (34.25–52.80) | 37.11 (28.55–45.67) | |
A: atrial systolic wave of transmitral flow velocity; AO: Aortic; Day 0: Before initiation of medication; Day 7: 7 days after the initiation of medication; Day 28: 28 days after the initiation of medication; Day 56: 56 days after the initiation of medication; Day 84: 84 days after the initiation of medication; E: early diastolic wave of transmitral flow; E decel time: deceleration time of early diastolic wave of transmitral flow, E/A: early diastolic to atrial systolic wave transmitral flow velocity; EF: ejection fraction; FS: fractional shortening; ICT: isovolumic contraction time; IRT: isovolumic relaxation time; IVSd: interventricular septal thickness in end-diastole; IVSs: interventricular septal thickness in end-systole; LA/AO: left atrium to aorta ratio; LVFWd: left ventricular free wall thickness in end-diastole; LVFWs: left ventricular free wall thickness in end-systole; LVIDd: left ventricular end-diastolic diameter; LVIDs: left ventricular end-systolic diameter; LVM: LV mass; PEP/ET: pre-ejection period and ejection time; RWT: relative wall thickness. Data are expressed as medians (range). * and ** Indicate significant difference compared to Day 0 values at P<0.05 and P<0.01, respectively.