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. 2021 Feb 9;34(6):642–652. doi: 10.1016/j.echo.2021.02.003

Table 2.

Univariate analysis of echocardiographic prediction of clinical events

Parameter Mortality, HR (95% CI) P Composite event, HR (95% CI) P
LV parameters
 LVEF, % 0.97 (0.95–1.03) .34 0.97 (0.94–1.00) .08
 Dichotomous LVEF < 50% 2.66 (1.1–5.8) .03 2.39 (1.1–4.8) .02
 LV S′, cm/sec 0.82 (0.63–1.04) .10 0.92 (0.76–1.10) .42
 LV end-diastolic diameter, mm 0.96 (0.93–1.00) .09 0.98 (0.95–1.01) .32
 LV end-systolic diameter, mm 0.96 (0.91–1.01) .13 1.00 (0.95–99) .91
 LV mass index, g/m2 1.00 (0.99–1.02) .54 1.00 (0.98–1.01) .87
 Left atrial volume index, mL/m2 1.01 (0.98–1.04) .27 1.02 (0.99–1.04) .12
Doppler parameters
 E-wave velocity, cm/sec 0.99 (0.98–1.01) .90 0.99 (0.98–1.01) .61
 A-wave velocity, cm/sec 1.00 (0.98–1.01) .99 1.00 (0.99–1.02) .31
 E/A ratio 0.98 (0.31–2.1) .98 0.53 (0.16–1.3) .19
 e′ septal, cm/sec 0.86 (0.69–1.05) .15 0.93 (0.79–1.08) .38
 e′ lateral, cm/sec 0.90 (0.78–1.04) .16 0.89 (0.79–1.00) .06
 E/e′ average ratio 1.02 (0.95–1.07) .59 1.00 (0.95–1.05) .82
 Right atrial pressure, mm Hg 0.94 (0.83–1.05) .34 1.03 (0.95–1.11) .44
 SVI, per 10 mL/m2 0.54 (0.36–0.82) .004 0.59 (0.41–0.85) .004
 Dichotomous SVI ≤ 23.0, ≤27.4 mL/m2 3.72 (1.69–8.39) .001 3.6 (1.8–7.1) .0004
 PAT, per 10 msec 0.87 (0.75–0.99) .05 0.81 (0.71–0.92) .007
 Dichotomous PAT < 77, 90 ms 2.74 (1.26–6.26) .01 4.6 (2.0–12.3) <.0001
RV parameters
 RV end-diastolic area index, cm2/m2 0.91 (0.79–1.06) .25 0.95 (0.83–1.08) .45
 RV end-systolic area index, cm2/m2 0.88 (0.70–1.08) .27 1.04 (0.88–1.18) .61
 RV fractional area change, % 1.02 (0.98–1.06) .17 0.99 (0.96–1.02) .86
 TAPSE, per cm 0.24 (0.12–0.48) <.0001 0.30 (0.16–0.55) .0001
 Dichotomous TAPSE < 1.9, 1.6 cm 4.1 (1.93–9.0) .0003 3.4 (1.7–6.7) .0001
 RV S′, cm/sec 0.83 (0.72–0.96) .01 0.87 (0.78–0.98) .02
 Tei index 1.48 (0.56–2.5) .33 1.46 (0.62–2.4) .31