Table 2.
Mixed-model regression of geographic atrophy area according to the presence or absence of subsequent exudative neovascular age-related macular degeneration.
| Number of eyes (participants) | Change per year in square root of GA area | Change per year in GA area | |||||
|---|---|---|---|---|---|---|---|
| Estimate (mm) | 95% CI (mm) | P* | Estimate (mm) | 95% CI (mm) | P* | ||
| Incident GA without subsequent exudative NV-AMD | 684 (561) | 0.29 | 0.27–0.30 | 0.037 | 1.13 | 1.05–1.20 | 0.004 |
| Incident GA with subsequent exudative NV-AMD | 73 (73) | 0.20 | 0.12–0.28 | 0.62 | 0.29–0.96 | ||
| Prevalent GA without subsequent exudative NV-AMD | 393 (321) | 0.28 | 0.26–0.29 | 0.37 | 1.41 | 1.31–1.51 | 0.87 |
| Prevalent GA with subsequent exudative NV-AMD | 63 (59) | 0.31 | 0.24–0.37 | 1.38 | 1.10–1.75 | ||
Abbreviations: CI = confidence interval; GA = geographic atrophy; NV-AMD = neovascular age-related macular degeneration.
P values for interaction between presence/absence of subsequent exudative neovascular age-related macular degeneration and years from first appearance of geographic atrophy.