Table 3:
Linear regression of cognition tests with albuminuria (≥ 30 mg/gram creatinine) and eGFR <60 ml/minute/1.73m2; β with 95% CI.
| SEVLT | DSST | Word Fluency Letters | Word Fluency Animal | |
|---|---|---|---|---|
| Model 1 | ||||
| ALB ≥30 | −0.06 (−0.62, 0.50) | −0.66 (−1.58, 0.26) | −0.14 (−0.47, 0.19) | −0.17 (−0.56, 0.21) |
| eGFR <60 | −1.04 (−2.35, 0.28) | −1.72 (−3.89, 0.46) | −0.46 (−1.24, 0.33) | −0.64 (−1.55, 0.27) |
| Model 2 | ||||
| ALB ≥30 | −0.19 (−0.73, 0.36 | −0.70 (−1.58, 0.16) | −0.12 (−0.45, 0.20) | −0.31 (−0.68, 0.07) |
| eGFR <60 | −1.09 (−2.37, 0.18) | −1.60 (−3.62, 0.42) | −0.40 (−1.16, 0.37) | −0.60 (−1.48, 0.28) |
| Model 3 | ||||
| ALB ≥ 30* | −0.17 (−0.72, 0.37) | −0.67 (−1.54, 0.19) | −0.12 (−0.45, 0.21) | −0.30 (−0.68, 0.72) |
| eGFR <60† | −1.03 (−2.31, 0.24) | −1.59 (−3.61, 0.43) | −0.38 (−1.15, 0.38) | −0.55 (−1.43, 0.33) |
Model 1: Adjusted for age, sex, race, Hispanic ethnicity, and an interaction term for age × sex.
Model 2: Model 1 plus education level, waist circumference, current smoking, alcohol status, history of stroke, HTN, hyperlipidemia and depression.
Model 3: Model 2 plus screening HbA1c, and either eGFR or UACR. In model 3 interaction terms were included for: sex (M vs F), age (<55 vs ≥55 years), lipid treatment and/or TC >240 (Y vs N), and by age × sex categories.
*
There were no significant interactions for < vs ≥ 30 mg/g creatinine.
†
There were no significant interactions for eGFR < vs ≥60 ml/minute/1.73m2.