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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Neurobiol Aging. 2020 Nov 13;98:173–184. doi: 10.1016/j.neurobiolaging.2020.10.014

Figure 1. Information regarding behavior tests and genotype confirmation.

Figure 1.

(A) A representative genotyping gel showing littermate genotypes for WT, heterozygous knock-in eIF4ES209A+/−, and homozygous knock-in eIF4ES209A−/− animals. (B) A representative western blot showing phosphorylated eIF4E protein in animals from the young WT and aged WT groups and none in eIF4ES209A knock-in young animals and eIF4ES209A knock-in aged animals. (C) A timeline showing when various behavior tasks were performed with the animal cohorts. SAT – spontaneous alternation task, NOR – novel object recognition.