Skip to main content
. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Neurobiol Aging. 2020 Nov 13;98:173–184. doi: 10.1016/j.neurobiolaging.2020.10.014

Figure 4. eIF4E phosphorylation mediates depressive-like and anxiety-like behavior in young and aged mice.

Figure 4.

(A) Immobile time (seconds) during the forced swim test. *p 0.0213, **p 0.0035. (B) Total distance traveled by the four groups (C) Number of entries made by each group into the open arms of the maze. No significant differences were found. (D) Percentage of time spent in the open arms of the maze relative to entire experiment duration. *p 0.0246. Individual values are separated by males (empty diamonds) and females (filled diamonds) and data are represented as means with SEM (n=10-21 per group). Two-way ANOVA with Bonferroni’s post-hoc was performed.