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. Author manuscript; available in PMC: 2022 Feb 19.
Published in final edited form as: J Mol Biol. 2020 Dec 31;433(4):166788. doi: 10.1016/j.jmb.2020.166788

Table 1. Top three Genetic Association Database (GAD) disease classes with significantly overrepresented RLM proteins.

Percentage was calculated based on number of RLM proteins (UniProt IDs) found in GAD (613 out of 615).

GAD disease class Number of proteins Percentage P-value Fisher exact test
Metabolic 236 38.5 2.8E-2 2.5E-2
Cancer 176 28.7 3.4E-6 2.5E-6
Neurological 156 25.4 5.4E-5 3.9E-5