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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Biomaterials. 2020 Dec 19;269:120607. doi: 10.1016/j.biomaterials.2020.120607

Figure 2. The osteogenic potential of MSC spheroids is enhanced in viscoelastic alginate.

Figure 2.

(A) Schematic depicting the use of MSCs in data presented in B and C. (B) DNA content of MSCs entrapped in viscoelastic and elastic VLVG alginate as monodisperse cells or spheroids (n=3). (C) Calcium deposition in gels loaded with monodisperse cells or MSC spheroids (n=3). (D) Schematic depicting the use of internal cues in E. (E) Calcium deposition in gels containing MSC spheroids after 14 days as a function of stimulus (n=4). (F) ALP activity in gels containing MSC spheroids after 5 days (n=3–4). Significance is denoted by alphabetical letterings. Groups with statistically significant differences do not share the same letters; “ns” denotes no significance among all groups.