Table 2.
Con | Con + Fer-1 | STZ | STZ + Fer-1 | |
---|---|---|---|---|
Body weight, g | 30.32 ± 3.61 | 29.33 ± 1.54 | 22.33 ± 1.73 | 26.81 ± 2.71 |
Kidney weight, mg | 188.40 ± 12.23 | 177.55 ± 7.65 | 197.05 ± 14.41 | 186.10 ± 11.49 |
Kidney/body weight, 10−3 | 6.28 ± 0.62 | 6.07 ± 0.43 | 8.84 ± 0.40 | 6.98 ± 0.46 |
Blood glucose, mg/dl | 126.20 ± 17.50 | 114.70 ± 18.87 | 524.00 ± 84.18 | 515.70 ± 94.51 |
Serum creatinine, mg/dl | 0.15 ± 0.04 | 0.13 ± 0.02 | 0.24 ± 0.09 | 0.20 ± 0.04 |
Serum BUN, mg/dl | 24.92 ± 2.42 | 23.00 ± 1.17 | 29.26 ± 2.80 | 26.90 ± 4.12 |
UACR, µg/mg | 0.015 ± 0.004 | 0.013 ± 0.001 | 0.053 ± 0.017 | 0.033 ± 0.010 |
Data are shown as mean ± standard deviation.
Con control, Fer-1 ferrostatin-1, DM diabetes mellitus, BUN blood urea nitrogen, UACR urine albumin to creatinine ratio.