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. 2021 Jan 26;7:625240. doi: 10.3389/fnut.2020.625240

Table 3.

Subgroup analysis assessing the effect of exercise as a moderator of the impact of intermittent fasting on body composition.

Moderators K Point estimate CI lower CI upper P-value Heterogeneity
Q-value P-value I-squared
Body Weight (kg)*
All studies
With exercise 8 −0.127 −0.312 0.059 0.182 5.330 0.021 52.046
Without exercise 17 −0.430 −0.609 −0.251 <0.001 87.986
Only Ramadan IF studies
With exercise 8 −0.127 −0.312 0.059 0.182 1.681 0.195 52.046
Without exercise 15 −0.276 −0.407 −0.146 <0.001 76.520
Body Weight (kg)**
All studies
With exercise 8 −0.386 −0.788 0.016 0.06 0.078 0.780 48.868
Without exercise 20 −0.320 −0.557 −0.082 0.008 72.681
Only Ramadan IF studies
With exercise 3 −0.419 −0.775 −0.064 0.021 0.457 0.499 0.000
Without exercise 3 −0.193 −0.744 0.357 0.491 0.000
Only nonRamadan IF studies
With exercise 5 −0.290 −1.048 0.469 0.454 0.016 0.900 69.912
Without exercise 17 −0.342 −0.603 −0.081 0.010 76.994
BMI (kg/m2)*
Only Ramadan IF studies
With exercise 4 −0.037 −0.181 0.106 0.612 4.417 0.036 0.000
Without exercise 12 −0.280 −0.456 −0.105 0.002 83.232
BMI (kg/m2)**
All studies
With exercise 5 −1.481 −2.581 −0.381 0.008 3.550 0.060 80.758
Without exercise 12 −0.396 −0.648 −0.144 0.002 61.208
Only Ramadan IF studies
With exercise 2 −0.572 −1.286 0.142 0.117 0.381 0.537 0.000
Without exercise 1 −0.189 −1.171 0.793 0.706 0.000
Only non-Ramadan IF studies
With exercise 3 −2.112 −3.634 −0.59 0.007 4.660 0.031 81.242
Without exercise 11 −0.411 −0.675 −0.147 0.002 64.721
FM (kg)*
All studies
With exercise 3 −0.552 −1.305 0.200 0.150 1.793 0.181 86.618
Without exercise 10 −1.146 −1.58 −0.712 <0.001 94.999
Only Ramadan IF studies
With exercise 2 −0.093 −0.346 0.161 0.473 3.404 0.065 13.04
Without exercise 6 −0.466 −0.772 −0.161 0.003 88.977
Only non-Ramadan IF studies
With exercise 1 −1.434 −2.117 −0.75 <0.001 2.764 0.096 0.000
Without exercise 4 −2.069 −2.376 −1.762 <0.001 23.425
FM (kg)**
All studies
With exercise 5 −0.779 −1.462 −0.095 0.026 1.279 0.258 65.227
Without exercise 19 −0.364 −0.584 −0.145 0.001 70.205
Only Ramadan IF studies
With exercise 1 −0.271 −1.263 0.721 0.593 0.002 0.966 0.000
Without exercise 1 −0.301 −1.286 0.685 0.549 0.000
Only non-Ramadan IF studies
With exercise 4 −0.897 −1.718 −0.077 0.032 1.487 0.223 71.000
Without exercise 18 −0.368 −0.594 −0.142 0.001 71.850
FM (%)*
All studies
With exercise 9 −0.386 −0.646 −0.125 0.004 0.448 0.503 76.645
Without exercise 6 −0.274 −0.470 −0.079 0.006 78.206
Only Ramadan IF studies
With exercise 7 −0.148 −0.267 −0.028 0.016 0.573 0.449 0.000
Without exercise 5 −0.236 −0.432 −0.04 0.018 79.574
Only non-Ramadan IF studies
With exercise 2 −1.271 −1.674 −0.869 <0.001 2.749 0.097 0.000
Without exercise 1 −0.686 −1.249 −0.124 0.017 0.000
FM (%)**
All studies
With exercise 5 −0.523 −0.968 −0.078 0.021 2.054 0.152 0.000
Without exercise 7 −0.153 −0.394 0.088 0.215 0.000
Only Ramadan IF studies
With exercise 3 −0.603 −1.172 −0.034 0.038 0.235 0.627 7.948
Without exercise 1 −0.321 −1.307 0.665 0.524 0.000
Only non-Ramadan IF studies
With exercise 2 −0.396 −1.112 0.32 0.278 0.432 0.511 0.000
Without exercise 6 −0.142 −0.391 0.107 0.263 0.000
Fat Free Mass (kg)*
All studies
With exercise 7 0.017 −0.101 0.135 0.779 0.178 0.673 0.000
Without exercise 8 −0.054 −0.358 0.251 0.731 88.948
Only Ramadan IF studies
With exercise 6 0.015 −0.106 0.137 0.806 3.282 0.070 0.000
Without exercise 4 −0.357 −0.742 0.027 0.068 89.896
Only non-Ramadan IF studies
With exercise 1 0.042 −0.438 0.523 0.862 1.333 0.248 0.000
Without exercise 4 0.346 0.160 0.532 <0.001 33.853
Fat Free Mass (kg)**
All studies
With exercise 6 0.015 −0.309 0.339 0.928 0.021 0.884 0.000
Without exercise 16 0.043 −0.138 0.223 0.643 48.726
Only Ramadan IF studies
With exercise 4 −0.234 −0.667 0.198 0.289 0.119 0.731 0.000
Without exercise 1 −0.046 −1.026 0.934 0.927 0.000
Only non-Ramadan IF studies
With exercise 2 0.337 −0.243 0.918 0.255 0.872 0.350 29.138
Without exercise 15 0.047 −0.140 0.234 0.624 52.128
*

Pre-post tests, IF intervention;

**

Pre-post tests, IF intervention vs. control; *Body Weight (kg), all studies (k = 25); **Body Weight (kg), all studies (k = 28); *Body Weight (kg), Ramadan IF studies (k = 23); **Body Weight (kg), Ramadan IF studies (k = 6); **Body Weight (kg), non-Ramadan IF studies (k = 22); **BMI, all studies (k = 17); *BMI, Ramadan IF studies (k = 16); **BMI, Ramadan IF studies (k = 3); **BMI, non-Ramadan IF studies (k = 14); *Fat Mass (kg), all studies (k = 13); **Fat Mass (kg), all studies (k = 24); *Fat Mass (kg), Ramadan IF studies (k = 8); **Fat Mass (kg), Ramadan IF studies (k = 2); *Fat Mass (kg), non-Ramadan IF studies (k = 5); **Fat Mass (kg), non-Ramadan IF studies (k = 22); *Fat Mass (%), all studies (k = 15); **Fat Mass (%), all studies (k = 12); *Fat Mass (%), Ramadan IF studies (k = 12); **Fat Mass (%), Ramadan IF studies (k = 4); *Fat Mass (%), non-Ramadan IF studies (k = 3); **Fat Mass (%), non-Ramadan IF studies (k = 2); *Fat Free Mass, all studies (k = 15), **Fat Free Mass, all studies (k = 22); *Fat Free Mass, Ramadan IF studies (k = 10); **Fat Free Mass, Ramadan IF studies (k = 5); *Fat Free Mass, non-Ramadan IF studies (k = 5); **Fat Free Mass, non-Ramadan IF studies (k = 17).

CI, confidence interval; BMI, body mass index; IF, intermittent fasting. The bold values are statistically significant values.