Table 5.
Microarray analysis of differential gene expression profile in peripheral blood cells (upregulated genes).
| Gene symbol | Gene description | Fold changea |
|---|---|---|
| Plk1 | Polo-like kinase 1 | 5.5 |
| Col11a1 | Collagen, type XI, alpha 1 | 4.9 |
| Tyro3 | Protein tyrosine kinase 3 | 4.9 |
| Klhdc9 | Kelch domain containing 9 | 4.8 |
| Casp2 | Caspase 2 | 4.5 |
| Entpd2 | Ectonucleoside triphosphate diphosphohydrolase 2 | 4.2 |
| Mcur1 | Mitochondrial calcium uniporter regulator 1 | 4.1 |
| Acoxl | Acyl-Coenzyme A oxidase-like | 4.0 |
| Lrrn2 | Leucine rich repeat protein 2, neuronal | 4.0 |
| Snrpc | U1 small nuclear ribonucleoprotein C | 3.9 |
| Klra20 | Killer cell lectin-like receptor subfamily A, member 20 | 3.9 |
| Pdgfra | Platelet derived growth factor receptor, alpha polypeptide | 3.9 |
| Etd | Embryonic testis differentiation | 3.8 |
| Zfp27 | Zinc finger protein 27 | 3.6 |
| Prdx6 | Peroxiredoxin 6 | 3.6 |
| Abcc8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 3.6 |
| Elovl2 | Elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 | 3.6 |
| Jun | Jun proto-oncogene | 3.5 |
| Rab3gap1 | RAB3 GTPase activating protein subunit 1 | 3.5 |
| Ccser2 | Coiled-coil serine rich 2 | 3.5 |
| Dsc1 | Desmocollin 1 | 3.5 |
| Mrps5 | Mitochondrial ribosomal protein S5 | 3.4 |
| Mga | MAX gene associated | 3.4 |
| TGF-β | transforming growth factor, beta 1 | 3.4 |
| Defa14 | Defensin, alpha, 14 | 3.3 |
| Cenpp | Centromere protein P | 3.3 |
| Rpl41 | Ribosomal protein L41 | 3.3 |
| Pdgfrl | Platelet-derived growth factor receptor-like | 3.3 |
| Lck | Lymphocyte protein tyrosine kinase | 3.2 |
| Vpreb3 | Pre-B lymphocyte gene 3 | 3.2 |
a
Polyherbal mixture treated vs. no treated animals.