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. 2021 Jan 26;10:585047. doi: 10.3389/fonc.2020.585047

Table 2.

The inhibitors partially or completely acting on TRAP1.

Drug Structure Properties Types of cancer Refs.
Gamitrinib-G4 graphic file with name fonc-10-585047-g003.jpg Hsp90 inhibitor and TRAP1 inhibitor Prostate cancer (74)
Shepherdin graphic file with name fonc-10-585047-g004.jpg Hsp90 inhibitor and TRAP1 inhibitor Glioblastoma, retinoblastoma (75, 76)
DN401 graphic file with name fonc-10-585047-g005.jpg Strong TRAP1 inhibitor but weak Hsp90 inhibitor Cervical cancer, liver cancer, brain cancer, kidney cancer, lung cancer, prostate cancer (77, 78)
Honokiol bis-dichloroacetate (HDCA) graphic file with name fonc-10-585047-g006.jpg TRAP1-specific inhibitor (79)