Figure 1.

Comparative HIM images of Vero E6 cells that were mock-infected and infected at MOI 1. (a_1–4) Mock-infected cells at different magnifications (FOV 200 µm, 45 µm, 15 µm, and 1.7 µm) and (b_1–4) cells infected at MOI 1 at different magnifications (FOV 250 µm, 45 µm, 15 µm, and 1.7 µm). The cell membrane is covered with the virus particles. (c_1–5) Determined virus particle diameter distributions. The inserted histograms show the respective image evaluation with normal distribution, mean value, and standard deviation. The average diameter of all evaluated images is 75 ± 13 nm.