Figure 5.

CCAT1 promotes the progression of NSCLC by interacting with miR-216a-5p. NCI-H1299 and A549 cells were transfected with si-NC, si-CCAT1, si-CCAT1 + anti-NC, or si-CCAT1 + anti-miR-216a-5p. (a) qRT-PCR analysis of the level of miR-216a-5p. (b) CCK-8 assay of cell proliferation. (c) Flow cytometry of cell apoptosis. (d) Western blot analysis of the levels of apoptosis-related proteins. (e and f) Transwell assay of cell migration and invasion abilities. *P < 0.05. (A color version of this figure is available in the online journal.)