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. Author manuscript; available in PMC: 2021 Feb 9.
Published in final edited form as: Chem Res Toxicol. 2019 Sep 3;32(9):1893–1899. doi: 10.1021/acs.chemrestox.9b00257

Table 2.

Mutational Profiles of NNN, DB[a,l]P, and Their Combination in lacI Mouse Tonguea

percentage of mutations
class NNN DB[a,l]P NNN + DB[a,l]P obs. NNN + DB[a,l]P exp.
G:A 18 16.7 42.0b 17.4
G:T 16 33.3 14.0 23.9
G:C 10 7.1 16.0 8.7
A:G 10 7.1 2.0 8.7
A:C 4 9.5 4.0 6.5
A:T 30 14.3 12.0 22.8
indel 12 11.9 10.0 12.0
100 100 100 100
a

To test whether there were any statistically significant differences between the observed and expected percentages for each mutation class, an “N − 1” chi-squared test was employed.

b

p < 0.05 for the difference between the observed and expected percentages.