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. 2021 Feb 9;8(1):e621. doi: 10.1002/ams2.621

Fig. 3.

Fig. 3

Time course of treatment of a 70‐year‐old man with respiratory failure due to empyema with bronchopleural fistula. Day 1, meropenem (MEPM) and vancomycin (VCM), chest tube, ventilation, and veno‐venous extracorporeal membrane oxygenation (VV‐ECMO) was initiated. Day 3, nutrition and rehabilitation was initiated. Day 4, endobronchial Watanabe spigot (EWS) was inserted at bronchi B8–10. Day 7, the patient was weaned off VV‐ECMO. Day 11, MEPM + VCM was changed to ampicillin/sulbactam (ABPC/SBT) and EWS was inserted at B4–6. Day 39, air leak disappeared and the chest tube was removed. Day 50, antibiotics completed. Day 95, oxygen inhalation completed. CRP, C‐reactive protein; P/F, PaO2/FIO2 ratio.