Table 1.
Prevalence of selected clinically relevant biomarkers in ISF, SBF and plasma in matched samples from 20 human participants.
| Biomarker | Prevalence of biomarker† | |||
|---|---|---|---|---|
| ID levela | Plasma | ISF | SBF | |
| Clinical Markers | ||||
| Bilirubin | 1 | 100% | 65% | 100% |
| Carnosine | 1 | 15% | 90% | 5% |
| Cortisol | 1 | 100% | 30% | 80% |
| Creatine | 1 | 100% | 100% | 100% |
| Creatinine | 1 | 100% | 100% | 100% |
| Homocysteine | 1 | 20% | 55% | 55% |
| Uric acid | 1 | 100% | 100% | 100% |
| Vitamins and cofactors | ||||
| All-trans-retinoic acid (Vitamin A) | 1 | 85% | 90% | 25% |
| Thiamine (Vitamin B1) | 1 | 80% | 40% | 95% |
| Lumazine (B2 synthesis intermediate) | 1 | 100% | 100% | 100% |
| Pantothenic acid (vitamin B5) | 1 | 90% | 65% | 100% |
| Lumichrome (Vitamin B5 derivative) | 1 | 5% | 100% | 10% |
| Pyridoxamine (Vitamin B6 form) | 1 | 85% | 55% | 100% |
| Pyridoxal (Vitamin B6 form) | 1 | 45% | 100% | 10% |
| 4-Pyridoxic acid (Vitamin B6 catabolic product) | 1 | 20% | 80% | 5% |
| Ascorbic acid (Vitamin C) | 1 | 15% | 100% | 95% |
| Ergocalciferol (Vitamin D2) | 1 | 5% | 100% | 0% |
| 7-Dehydrocholesterol (Provitamin D3) | 1 | 95% | 100% | 100% |
| Nucleotide-related metabolism | ||||
| Hypoxanthine | 1 | 100% | 100% | 100% |
| NAD | 1 | 15% | 25% | 70% |
| Uridine | 1 | 95% | 100% | 100% |
| Xanthine | 1 | 85% | 100% | 100% |
| Fatty acids | ||||
| Myristic acid (C14:0) | 1 | 90% | 100% | 75% |
| Palmitoleic acid (C16:1) | 1 | 90% | 100% | 55% |
| Stearic acid (C18:0) | 1 | 75% | 100% | 15% |
| Arachidic acid (C20:0) | 1 | 100% | 100% | 100% |
| Sterol metabolism | ||||
| Cholic acid | 1 | 90% | 95% | 100% |
| Glycocholic acid | 1 | 100% | 65% | 100% |