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. 2021 Feb 9;19:60. doi: 10.1186/s12967-021-02734-4

Table 2.

List of phosphorylated substrates in cell lines treated with exogenous, purified DnaK

Phosphorylated substrate Cell line
HCT116 PC3 SHSY5Y not differentiated SHSY5Y differentiated
β-Catenin x
CREB1
HSP27 S78/S82 S78, S82 S78, S82
HSP60 x x
c-JUN S63 S63
eNOS S1177
p27 T198 T198
p53 S15 S15, S46, S392 S15, S46, S392
PLC-γ1 Y783
PRAS40 T246
STAT2 Y689
STAT3 Y705, S727
STAT5a xY699 xY694

Numbers represents phosphorylation sites

S serine, T threonine, Y tyrosine, P protein phosphorylated, unknown site