Table 2.

Cohort 1. P-values and Akaike information criterion (AIC) from binary logistic regression. Area under the curve (AUC), 95% confidence intervals (95% CI) and differences between AUCs measured with DeLong test from receiver operating characteristic (ROC) analysis. APOE stands for presence of at least one APOE ε4 allele

Cohort 1	p	AIC	AUC	95%CI	p value for difference with model containing N-224 alone
N-224	< 0.0001	54.4	0.851	0.751–0.952	–
Age	< 0.0001	53.6	0.853	0.743–0.963	ns
T-tau	< 0.0001	39.9	0.931	0.870–0.993	0.005
P-tau181	< 0.0001	43.9	0.916	0.846–0.987	ns
N-224+T-tau	< 0.0001	38.8	0.944	0.889–0.999	ns
N-224+P-tau181	< 0.0001	47.2	0.919	0.850–0.987	ns
N-224+APOE	< 0.0001	54.1	0.873	0.782–0.964	ns
Aβ42+P-tau181	< 0.0001	17.8	0.991	0.973–1.010	0.004